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253847

Sigma-Aldrich

2,3,4-Trihydroxybenzoic acid

97%

Synonym(s):

Pyrogallol-4-carboxylic acid

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About This Item

Linear Formula:
(HO)3C6H2CO2H
CAS Number:
Molecular Weight:
170.12
Beilstein/REAXYS Number:
2210807
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

97%

mp

~205 °C (dec.) (lit.)

SMILES string

OC(=O)c1ccc(O)c(O)c1O

InChI

1S/C7H6O5/c8-4-2-1-3(7(11)12)5(9)6(4)10/h1-2,8-10H,(H,11,12)

InChI key

BRRSNXCXLSVPFC-UHFFFAOYSA-N

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General description

DPPH radical-scavenging ability of 2,3,4-trihydroxybenzoic acid has been evaluated.

Application

2,3,4-Trihydroxybenzoic acid has been used as:
  • reagent during catalytic spectrophotometric determination of vanadium in natural and sea waters
  • internal standard in separation of phenolic acids by HPLC with photodiode array detection

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rebecca J Robbins et al.
Journal of chromatography. A, 1038(1-2), 97-105 (2004-07-06)
A quantitative high-performance liquid chromatography-photodiode array detection method separating 16 phenolic acids was achieved. Six columns and several mobile phases were investigated. Resolution was achieved with a high-purity silica Phenomenex Luna C18 column (150 mm x 4.6 mm, 5 microm)
David V McCalley
Journal of chromatography. A, 1483, 71-79 (2017-01-11)
Trifluoracetic acid (TFA) added to the aqueous acetonitrile mobile phase induces some unexpected changes in the ionic component of retention in hydrophilic interaction separations when using Type B silica and amide-bonded silica columns. TFA use results in anion exchange properties
F Ramezani Ali Akbari et al.
Acta endocrinologica (Bucharest, Romania : 2005), 15(2), 187-194 (2019-09-12)
Endothelial dysfunction and diabetic cardiomyopathy are critical complications of diabetes. Gallic acid (GA) plays a significant role in cardiovascular disorders resulted from diabetes. In addition, increased plasma miR-24, miR-126 associated with endothelial dysfunction. The current study was designed to assess
A A Mohamed et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 17(6), 769-773 (2001-11-16)
A new, simple, sensitive and selective catalytic method is developed for the determination of vanadium in natural and sea waters. The method is based on the catalytic effect of V(V) and/or V(IV) on the bromate oxidative-coupling reaction of metol with
Yuan Gao et al.
Journal of the science of food and agriculture, 99(7), 3555-3562 (2019-01-11)
Sweet cherries (Prunus avium L.) are rich in polyphenols and have high antioxidant potential. This study deals with the use of ultra-performance liquid chromatography-tandem mass spectrometry on five cherry cultivars, namely Caihong, Sunburst, Summit, 23-51 and Valeri, to determine the

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