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211281

Sigma-Aldrich

9-Phenanthrol

technical grade

Synonym(s):

9-Hydroxyphenanthrene

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1 G
$191.90
5 G
$324.50

About This Item

Empirical Formula (Hill Notation):
C14H10O
CAS Number:
484-17-3
Molecular Weight:
194.23
EC Number:
207-602-4
MDL number:
MFCD00082298
UNSPSC Code:
12352100
PubChem Substance ID:
24852666
NACRES:
NA.22

$191.90

List Price$202.00
Web-Only Promotion

Available to ship onApril 29, 2025Details

Request a Bulk Order

grade

technical grade

mp

139-143 °C (lit.)

SMILES string

Oc1cc2ccccc2c3ccccc13

InChI

1S/C14H10O/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9,15H

InChI key

DZKIUEHLEXLYKM-UHFFFAOYSA-N

application

9-Phenanthrol was used to investigate C K-edge and O K-edge near-edge X-ray absorption fine structure (NEXAFS) spectra of single-wall carbon nanotubes[1].

Biochem/physiol Actions

9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel[2].

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000259976
0000242173
0000202079
0000202076
BGBC2991V

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Ana Mrejeru et al.
The Journal of physiology, 589(Pt 10), 2497-2514 (2011-04-14)
Nigral dopamine neurons are transiently activated by high frequency glutamatergic inputs relaying reward-predicting sensory information. The tonic firing pattern of dopamine cells responds to these inputs with a transient burst of spikes that requires NMDA receptors. Here, we show that
T Grand et al.
British journal of pharmacology, 153(8), 1697-1705 (2008-02-26)
TRPM4 and TRPM5 are calcium-activated non-selective cation channels with almost identical characteristics. TRPM4 is detected in several tissues including heart, kidney, brainstem, cerebral artery and immune system whereas TRPM5 expression is more restricted. Determination of their roles in physiological processes
Eric C Lin et al.
Frontiers in cellular neuroscience, 11, 182-182 (2017-07-18)
Temporal lobe epilepsy is characterized by recurrent seizures in one or both temporal lobes of the brain; some
A Kuznetsova et al.
Journal of the American Chemical Society, 123(43), 10699-10704 (2001-10-25)
Single-walled nanotubes (SWNTs) produced by plasma laser vaporization (PLV) and containing oxidized surface functional groups have been studied for the first time with NEXAFS. Comparisons are made to SWNTs made by catalytic synthesis over Fe particles in high-pressure CO, called
R Guinamard et al.
British journal of pharmacology, 171(7), 1600-1613 (2014-01-18)
The phenanthrene-derivative 9-phenanthrol is a recently identified inhibitor of the transient receptor potential melastatin (TRPM) 4 channel, a Ca(2+) -activated non-selective cation channel whose mechanism of action remains to be determined. Subsequent studies performed on other ion channels confirm the
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