Skip to Content
MilliporeSigma
All Photos(2)

Documents

180386

Sigma-Aldrich

2,2,2-Trifluoroethylamine hydrochloride

98%

Synonym(s):

2-Amino-1,1,1-trifluoroethane hydrochloride

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
CF3CH2NH2 · HCl
CAS Number:
373-88-6
Molecular Weight:
135.52
Beilstein/REAXYS Number:
3652103
EC Number:
206-771-1
MDL number:
MFCD00012875
UNSPSC Code:
12352100
PubChem Substance ID:
24850866
NACRES:
NA.22

assay

98%

mp

220-222 °C (subl.) (lit.)

SMILES string

Cl.NCC(F)(F)F

InChI

1S/C2H4F3N.ClH/c3-2(4,5)1-6;/h1,6H2;1H

InChI key

ZTUJDPKOHPKRMO-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

2,2,2-Trifluoroethylamine hydrochloride was used in the derivatization of aqueous carboxylic acids to the corresponding 2,2,2-trifluoroethylamide derivative.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Quincy LaRon Ford et al.
Journal of chromatography. A, 1145(1-2), 241-245 (2007-02-20)
We report a technique for the rapid, room temperature derivatization of aqueous carboxylic acids to the corresponding 2,2,2-trifluoroethylamide derivative. 3-Ethyl-1-[3-(dimethylamino)propyl]carbodiimide hydrochloride (EDC) and 2,2,2-trifluoroethylamine hydrochloride (TFEA) were added to aqueous samples of several acids of interest in environmental analytical chemistry
Yoshikazu Hattori et al.
Journal of biomolecular NMR, 68(4), 271-279 (2017-08-02)
The preparation of stable isotope-labeled proteins is important for NMR studies, however, it is often hampered in the case of eukaryotic proteins which are not readily expressed in Escherichia coli. Such proteins are often conveniently investigated following post-expression chemical isotope

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service