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17988

Sigma-Aldrich

DL-β-Leucine

≥98.0% (NT)

Synonym(s):

(±)-3-Amino-4-methylpentanoic acid, (±)-3-Amino-4-methylvaleric acid

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About This Item

Empirical Formula (Hill Notation):
C6H13NO2
CAS Number:
Molecular Weight:
131.17
Beilstein/REAXYS Number:
1747371
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

assay

≥98.0% (NT)

application(s)

peptide synthesis

SMILES string

CC(C)C(N)CC(O)=O

InChI

1S/C6H13NO2/c1-4(2)5(7)3-6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)

InChI key

GLUJNGJDHCTUJY-UHFFFAOYSA-N

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Evaristo Peggion et al.
Biochemistry, 41(25), 8162-8175 (2002-06-19)
The 1-34 N-terminal fragments of human parathyroid hormone (PTH) and PTH-related protein (PTHrP) elicit the full spectrum of bone-relevant activities characteristic of the intact hormones. The structural elements believed to be required for receptor binding and biological activity are two
J M Poston
The Journal of biological chemistry, 255(21), 10067-10072 (1980-11-10)
Circulating levels of beta-leucine are elevated in the cobalamin-deficient state of pernicious anemia. Levels of leucine, on the other hand, are much lower. It is proposed that leucine 2,3-aminomutase, the cobalamin-dependent enzyme that catalyzes the interconversion of leucine and beta-leucine
Cobalamin-dependent leucine and beta-leucine synthesis in higher animals.
Nutrition reviews, 39(6), 244-246 (1981-06-01)
The synthesis and detection of beta leucines.
S R Sylvester et al.
Proceedings of the Western Pharmacology Society, 24, 117-117 (1981-01-01)
N E Ward et al.
The Journal of nutrition, 118(2), 159-164 (1988-02-01)
This study was designed to investigate a postulated relationship between vitamin B-12 and leucine metabolism in mature domestic chickens. Plasma amino acid analysis revealed the presence of beta-leucine at a concentration of 60 to 80 mumol/l. After 425 d on

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