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174823

Sigma-Aldrich

4-Quinolinecarboxylic acid

97%

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1 G
$49.40

About This Item

Empirical Formula (Hill Notation):
C10H7NO2
CAS Number:
Molecular Weight:
173.17
Beilstein/REAXYS Number:
5224
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

$49.40


Available to ship onMay 01, 2025Details


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Quality Level

assay

97%

mp

254-255 °C (lit.)

functional group

carboxylic acid

SMILES string

OC(=O)c1ccnc2ccccc12

InChI

1S/C10H7NO2/c12-10(13)8-5-6-11-9-4-2-1-3-7(8)9/h1-6H,(H,12,13)

InChI key

VQMSRUREDGBWKT-UHFFFAOYSA-N

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application

4-Quinolinecarboxylic acid was used in the coupling reaction with diamine linker[1]. A 4-quinolinecarboxylic acid analogue, brequinar sodium was used to inhibit dihydroorotate dehydrogenase and the de novo biosynthesis of pyrimidine[2].

Biochem/physiol Actions

4-Quinolinecarboxylic acid showed anti-tumor activity against L1210 leukemia and B16 melanoma[3].

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Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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M-J Chen et al.
European review for medical and pharmacological sciences, 23(10), 4360-4367 (2019-06-08)
The aim of this work was to explore whether lncRNA-MEG3 could serve as a serum biomarker for diagnosing chronic hepatitis B (CHB) and improve the early diagnostic and treatment efficacies. Serum level of lncRNA-MEG3 in CHB patients and healthy controls
A J Dobson et al.
Acta crystallographica. Section C, Crystal structure communications, 54 ( Pt 12), 1883-1885 (1999-01-28)
The title acid, C10H7NO2, crystallized in the centrosymmetric space group P2(1)/c with one molecule in the asymmetric unit. There is a single hydrogen bond. O-H...N, with a donor-acceptor distance of 2.596 (1) A. The carboxylic H atom is ordered. The
A J Dobson et al.
Acta crystallographica. Section C, Crystal structure communications, 55 ( Pt 6), 935-937 (1999-07-17)
The title acid, C10H7NO2.2H2O, crystallized in the non-centrosymmetric space group Cc with one zwitterionic organic molecule and two water molecules in the asymmetric unit. One N-H...O and four O-H...O hydrogen bonds are present in this structure, with donor-acceptor distances ranging
[3-hydroxy-2-phenylcinchonine acid therapy of rheumatic fever].
M IVERSEN
Ugeskrift for laeger, 113(26), 851-855 (1951-06-28)
J Strigácová et al.
Folia microbiologica, 45(4), 305-309 (2001-05-12)
The antimicrobial and morphogenetic effects of fourteen newly synthesized 2-substituted derivatives of quinoline-4-carboxylic acid and quinoline-4-carboxamide were studied using G+ and G- bacteria, yeasts and filamentous fungi. The highest antimicrobial effects were found with substituted quinoline-4-carboxylic acid derivatives. Quinoline-4-carboxamides only

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