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15140

Sigma-Aldrich

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride

≥97.0% (AT)

Synonym(s):

BOP-Cl, Phosphoric acid bis(2-oxooxazolidide) chloride

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5 G
$93.60
25 G
$366.00

About This Item

Empirical Formula (Hill Notation):
C6H8ClN2O5P
CAS Number:
Molecular Weight:
254.56
Beilstein/REAXYS Number:
3654596
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

$93.60


Available to ship onMay 02, 2025Details


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Quality Level

assay

≥97.0% (AT)

form

solid

mp

191 °C (dec.) (lit.)

SMILES string

ClP(=O)(N1CCOC1=O)N2CCOC2=O

InChI

1S/C6H8ClN2O5P/c7-15(12,8-1-3-13-5(8)10)9-2-4-14-6(9)11/h1-4H2

InChI key

KLDLRDSRCMJKGM-UHFFFAOYSA-N

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application

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride was used in the preparation of hexadepsipeptide[1].

Other Notes

Reagent for activating the carboxylic group, synthesis of amides [2][3]; Esters [4]; Peptides [5]

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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S. Danishefsky et al
Tetrahedron Letters, 25, 4203-4203 (1984)
Zhao Yanbin et al.
Biochemical and biophysical research communications, 516(1), 102-111 (2019-06-16)
Here, we firstly examined the proliferation and invasion capacities of different osteosarcoma (OS) cell lines, and analyzed the profiling of the differentially expressed circular RNAs(circRNAs). Then, we identified a novel circRNA(circ_101356/circ_0004846, we named circSAMD4 in the present study) and found
E.J. Corey et al.
Journal of the American Chemical Society, 104, 6818-6818 (1982)
R.D. Tung et al.
Journal of the American Chemical Society, 107, 4342-4342 (1985)
T Miyazawa et al.
International journal of peptide and protein research, 40(1), 49-53 (1992-07-01)
In segment couplings by the mixed anhydride method using isobutyloxycarbonyl chloride, the use of copper(II) chloride as an additive suppressed racemization completely in the same manner as in the carbodiimide method reported previously. This was confirmed by employing a number

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