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139181

Sigma-Aldrich

Bromodichloromethane

≥97%

Synonym(s):

Dichlorobromomethane

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10 G
$59.30
50 G
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100 G
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About This Item

Linear Formula:
BrCHCl2
CAS Number:
75-27-4
Molecular Weight:
163.83
Beilstein/REAXYS Number:
1697005
EC Number:
200-856-7
MDL number:
MFCD00000824
UNSPSC Code:
12352100
PubChem Substance ID:
24848395
NACRES:
NA.22

$59.30

Available to ship onApril 29, 2025Details

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Quality Level

100

assay

≥97%

form

liquid

contains

potassium carbonate as stabilizer

refractive index

n20/D 1.497 (lit.)

bp

87 °C (lit.)

mp

−55 °C (lit.)

solubility

water: insoluble

density

1.98 g/mL at 25 °C (lit.)

functional group

bromo
chloro

SMILES string

ClC(Cl)Br

InChI

1S/CHBrCl2/c2-1(3)4/h1H

InChI key

FMWLUWPQPKEARP-UHFFFAOYSA-N

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application

Bromodichloromethane was used to investigate the in vivo genotoxicity of chlorodibromomethane, bromodichloromethane and bromoform in mice[1].

Biochem/physiol Actions

Bromodichloromethane (BDCM) induces steatohepatitic injury in human liver[2]. BDCM induces the cell proliferation in different tissues[3] and kidney damage by renal tuble cell proliferation[4] in male F344 rats.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX5571
MKCR7815
MKCR8852
MKCR3227
MKCQ9555

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K J Stocker et al.
Mutagenesis, 12(3), 169-173 (1997-05-01)
Chlorination of drinking water results in the formation of chlorodibromomethane, bromodichloromethane and bromoform. These trihalomethanes have all shown evidence of genotoxicity in bacterial and mammalian cell systems in vitro and some evidence of carcinogenicity in rodents. Chlorodibromomethane and bromodichloromethane have
Richard J Summerhayes et al.
Epidemiology (Cambridge, Mass.), 23(1), 15-22 (2011-12-14)
Trihalomethanes in drinking water have been associated with higher occurrence of small-for-gestational-age (SGA) births, although results have been inconsistent. We geocoded residential address for mother of live, singleton, term births to 33 water distribution systems in a large metropolitan area
Ratanesh Kumar Seth et al.
Toxicology and applied pharmacology, 274(1), 42-54 (2013-11-12)
Environmental toxins induce a novel CYP2E1/leptin signaling axis in liver. This in turn activates a poorly characterized innate immune response that contributes to nonalcoholic steatohepatitis (NASH) progression. To identify the relevant subsets of T-lymphocytes in CYP2E1-dependent, environment-linked NASH, we utilized
Suvarthi Das et al.
Toxicology and applied pharmacology, 269(3), 297-306 (2013-02-27)
Today's developed world faces a major public health challenge in the rise in the obese population and the increased incidence in fatty liver disease. There is a strong association among diet induced obesity, fatty liver disease and development of nonalcoholic
Teresa L Leavens et al.
Toxicological sciences : an official journal of the Society of Toxicology, 99(2), 432-445 (2007-07-28)
Exposure to bromodichloromethane (BDCM), one of the most prevalent disinfection byproducts in drinking water, can occur via ingestion of water and by dermal absorption and inhalation during activities such as bathing and showering. The objectives of this research were to
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