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129593

Sigma-Aldrich

Malonamide

97%

Synonym(s):

Malonodiamide

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100 G
$92.34

About This Item

Linear Formula:
CH2(CONH2)2
CAS Number:
Molecular Weight:
102.09
Beilstein/REAXYS Number:
1751401
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

$92.34

List Price$97.20Save 5%
Web-Only Promotion

Available to ship onMay 01, 2025Details


Request a Bulk Order

Quality Level

assay

97%

form

solid

mp

172-175 °C (lit.)

fluorescence

λex 367 nm; λem 445 nm (α-keto acid adduct)

SMILES string

NC(=O)CC(N)=O

InChI

1S/C3H6N2O2/c4-2(6)1-3(5)7/h1H2,(H2,4,6)(H2,5,7)

InChI key

WRIRWRKPLXCTFD-UHFFFAOYSA-N

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General description

The malonamide derivatives are obtained by the one-pot, five-component condensation reaction of isocyanide, Meldrum′s acid, arylidene malononitrile, and two amine molecules in CH2Cl2[1].

Application

The malonamide-based ionic liquid extractant was used in the extraction of europium(iii) and other trivalent rare-earth ions from nitric acid medium[2].

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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P J Blackall et al.
Veterinary microbiology, 11(3), 301-306 (1986-03-01)
The effect of using two different techniques for the detection of substrate alkalinization by Bordetella avium and reference strains of Alcaligenes faecalis and B. bronchiseptica was evaluated. The techniques used were those described by Otto and Pickett and Hinz et
Zhong-Liu Wu et al.
The Journal of organic chemistry, 68(6), 2479-2482 (2003-03-15)
A variety of alpha,alpha-disubstituted malonamides undergo enantioselective hydrolysis with Rhodococcus sp. CGMCC 0497 to give challenging enantiopure alpha,alpha-disubstituted malonamic acids with up to >99% enantiomeric excesses and 98% chemical yields. The enantioselectivity originated from the effects of a highly enantioselective
Oscar Saavedra et al.
Bioorganic & medicinal chemistry letters, 19(24), 6836-6839 (2009-11-10)
A family of thieno[3,2-b]pyridine based small molecule inhibitors of c-Met and VEGFR2 were designed based on lead structure 2. These compounds were shown to have IC(50) values in the low nanomolar range in vitro and were efficacious in human tumor
S A Ansari et al.
Journal of hazardous materials, 161(2-3), 1323-1329 (2008-06-11)
A new chelating polymeric extraction chromatographic resin was prepared by chemical anchoring of N,N'-dimethyl-N,N'-dibutyl malonamide (DMDBMA) with chloromethylated Merrifield resin((R)). The grafted resin exhibited stronger binding for hexavalent and tetravalent actinides such as U(VI), Th(IV) and Pu(IV) over trivalent actinides
Suban K Sahoo et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 63(3), 574-586 (2005-07-19)
A new dipodal ligand, N,N'-bis{2-[(2-hydroxybenzylidine)amino]ethyl}malonamide (BHAEM) was synthesized by Schiff base condensation of N,N'-bis(2-aminoethyl)malonamide with two equivalent of salicylaldehyde and characterized on the basis of elemental analyses and various spectral (UV-vis, IR, (1)H NMR and (13)C NMR) data. The complexation

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