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117323

Sigma-Aldrich

4,4′-Methylene-bis(2-chloroaniline)

85%

Synonym(s):

2,2′-Dichloro-4,4′-methylenedianiline, 4,4′-Diamino-3,3′-dichlorodiphenylmethane

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$151.05
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$392.00

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250 G
$151.05
1 KG
$392.00

About This Item

Linear Formula:
CH2[C6H3(Cl)NH2]2
CAS Number:
Molecular Weight:
267.15
Beilstein/REAXYS Number:
1882318
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

$151.05

List Price$159.00
Web-Only Promotion

Available to ship onApril 29, 2025Details


Request a Bulk Order

Quality Level

assay

85%

form

solid

bp

202-214 °C/0.3 mmHg (lit.)

mp

102-107 °C (lit.)

SMILES string

Nc1ccc(Cc2ccc(N)c(Cl)c2)cc1Cl

InChI

1S/C13H12Cl2N2/c14-10-6-8(1-3-12(10)16)5-9-2-4-13(17)11(15)7-9/h1-4,6-7H,5,16-17H2

InChI key

IBOFVQJTBBUKMU-UHFFFAOYSA-N

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Muta. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup


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E B Murray et al.
Reviews on environmental health, 20(3), 163-176 (2005-12-13)
Cytogenetic end-points used to estimate risk of genotoxic events in workers include the measurement of micronuclei (MN) in exfoliated cells, lymphocytes, and other tissues. Micronuclei are chromatin-containing bodies outside the cell nucleus resulting from contaminant-induced DNA damage. A review of
4,4'-Methylenebis(2-chloroaniline).
Report on carcinogens : carcinogen profiles, 10, 149-151 (2004-08-26)
Chiu-Shong Liu et al.
Environmental health perspectives, 113(6), 771-774 (2005-06-03)
A 52-year-old male chemical worker was admitted to the hospital with a history of paroxysmal microscopic hematuria for about 2 years and nocturia with gross hematuria about five times per night for 2 months. He was a nonsmoker and denied
Wei-Chung Shih et al.
Rapid communications in mass spectrometry : RCM, 21(24), 4073-4078 (2007-11-17)
Analysis of 4,4'-methylenebis(2-cholroaniline) (MOCA) or its metabolites in urine has been considered as the appropriate method to assess MOCA exposures through inhalation and skin absorption. MOCA and its metabolite, N-acetyl 4,4'-methylenebis(2-chloroaniline) (acetyl-MOCA), are analyzed using methods either limited by sensitivity
4,4'-Methylenebis(2-chloroaniline).
Report on carcinogens : carcinogen profiles, 11, III167-III168 (2004-01-01)

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