100870
Bis(4-chlorophenyl)acetic acid
98%
Synonym(s):
4,4′-DDA
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All Photos(2)
About This Item
Linear Formula:
(ClC6H4)2CHCO2H
CAS Number:
Molecular Weight:
281.13
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
Recommended Products
assay
98%
mp
167-169 °C (lit.)
functional group
carboxylic acid
chloro
SMILES string
OC(=O)C(c1ccc(Cl)cc1)c2ccc(Cl)cc2
InChI
1S/C14H10Cl2O2/c15-11-5-1-9(2-6-11)13(14(17)18)10-3-7-12(16)8-4-10/h1-8,13H,(H,17,18)
InChI key
YIOCIFXUGBYCJR-UHFFFAOYSA-N
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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W K Nichols et al.
Drug metabolism and disposition: the biological fate of chemicals, 23(5), 595-599 (1995-05-01)
Isolated rabbit Clara cells and a transformed human bronchial epithelial cell line, BEAS-2B, were used to investigate the mechanism of cytotoxicity of 1,1-dichloro-2,2-bis(p-chlorophenyl)ethane (DDD), a persistent insecticide and stable metabolite of 1,1,1-trichloro-2,2- bis(p-chlorophenyl)ethane. Both BEAS-2B cells and rabbit Clara cells
H van Dijk et al.
Methods and findings in experimental and clinical pharmacology, 8(3), 189-193 (1986-03-01)
A novel, sensitive system to determine immunological adjuvant activity is presented. It is based on the direct haemagglutinin response of mice to neuraminidase-treated sheep red blood cells (asialo-SRBC) seven days after i.p. immunization. For two model adjuvants it is shown
Development of an enzyme-linked immunosorbent assay for the quantification of DDA (2,2-bis(p-chlorophenyl) acetic acid) in urine.
B D Banerjee
Bulletin of environmental contamination and toxicology, 38(5), 798-804 (1987-05-01)
Zhenshan Chen et al.
International journal of toxicology, 28(6), 528-533 (2009-12-08)
DDT metabolism in humans yields DDA as the principal urinary metabolite and potential exposure biomarker. A method for DDA analysis in human urine was developed using pentafluorobenzyl bromide and diisopropylethyl amine. Dried hexane extracts were reacted for 1 hour at
C Zhang et al.
Pharmacological research, 38(6), 413-417 (1999-02-17)
The cardiovascular activity of 14-deoxy-11,12-didehydroandrographolide (DDA) from Andrographis paniculata (Burm.f.) Nees (Acanthaceae) was elucidated in anaesthetised Sprague-Dawley (SD) rats and isolated rat right atria. In anaesthetised rats, DDA produced significant falls in mean arterial blood pressure (MAP) and heart rate
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