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UNG

uracil-DNA glycosylase

Synonyms:
DGU, HIGM4, HIGM5, UDG, UNG1, UNG15, UNG2
Species:
UniProtKB ID:
Gene ID:
  • Human(7374) Summary: This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010]
  • Mouse(22256) uracil DNA glycosylase
  • Rat(304577) uracil-DNA glycosylase
  • Thale Cress(821394) uracil dna glycosylase
  • fruit fly(44538) uniungula
  • dog(486315) uracil-DNA glycosylase
  • chicken(374010) uracil-DNA glycosylase
  • cow(511381) uracil-DNA glycosylase
  • domestic cat(101094053) uracil-DNA glycosylase
  • sheep(101115316) uracil-DNA glycosylase
  • naked mole-rat(101717051) uracil-DNA glycosylase
  • domestic guinea pig(100730581) uracil-DNA glycosylase

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-UNG1 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-Uracil-DNA glycosylase Antibody, clone 8G10.1, clone 8G10.1, from mouse,
Species Reactivity
chimpanzee, human, monkey
Application
immunohistochemistry
western blot
Anti-UNG antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-UNG antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-UNG1 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human UNG,
Species
human