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TRADD

TNFRSF1A-associated via death domain

Synonyms:
Hs.89862
Species:
UniProtKB ID:
Gene ID:
  • Human(8717) Summary: The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]
  • Mouse(71609) TNFRSF1A-associated via death domain
  • Rat(246756) TNFRSF1A-associated via death domain
  • naked mole-rat(101721567) TNFRSF1A-associated via death domain
  • domestic guinea pig(100732953) TNFRSF1A-associated via death domain
  • sheep(101111042) TNFRSF1A-associated via death domain
  • Zebrafish(58130) tnfrsf1a-associated via death domain
  • cow(504707) TNFRSF1A-associated via death domain
  • dog(611262) TNFRSF1A-associated via death domain
  • chicken(415700) TNFRSF1A-associated via death domain
  • domestic cat(101097773) TNFRSF1A-associated via death domain

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TRADD antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Monoclonal Anti-TRADD, (C-terminal) antibody produced in mouse, clone 3G1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-TRADD antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-TRADD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TRADD,
Species
human