TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
Synonyms:
DDP, DDP1, DFN1, MTS, TIM8
Species:
Human TIMM8A (1678), domestic cat TIMM8A (101087820), dog TIMM8A (480986), chicken TIMM8A (422190), Zebrafish timm8a (445243), domestic guinea pig Timm8a (100715801), naked mole-rat Timm8a (101715600), cow TIMM8A (515109), sheep TIMM8A (101105475)
UniProtKB ID:
Gene ID:
- Human(1678) Summary: This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Mar 2009]
- domestic cat(101087820) translocase of inner mitochondrial membrane 8 homolog A (yeast)
- dog(480986) translocase of inner mitochondrial membrane 8 homolog A (yeast)
- chicken(422190) translocase of inner mitochondrial membrane 8 homolog A (yeast)
- Zebrafish(445243) translocase of inner mitochondrial membrane 8 homolog A (yeast)
- domestic guinea pig(100715801) translocase of inner mitochondrial membrane 8 homolog A (yeast)
- naked mole-rat(101715600) translocase of inner mitochondrial membrane 8 homolog A (yeast)
- cow(515109) translocase of inner mitochondrial membrane 8 homolog A (yeast)
- sheep(101105475) translocase of inner mitochondrial membrane 8 homolog A (yeast)
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TIMM8A antibody produced in mouse, clone 2F11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TIMM8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
esiRNA
Product Number
Description
Species