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TGM2

transglutaminase 2

Synonyms:
G-ALPHA-h, GNAH, TG2, TGC
Species:
UniProtKB ID:
Gene ID:
  • Human(7052) Summary: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(21817) transglutaminase 2, C polypeptide
  • Rat(56083) transglutaminase 2, C polypeptide
  • dog(485867) transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
  • domestic cat(101098215) transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
  • chicken(396432) transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
  • domestic guinea pig(100379228) transglutaminase 2, C polypeptide
  • naked mole-rat(101699097) transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
  • cow(281528) transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
  • sheep(101123140) transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)

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ELISA

Product Number
Description
Species
Human Transglutaminase 2 ELISA, for serum, plasma and cell culture supernatants,
Species
human
Transglutaminase Assay Kit, sufficient for assays in two 96-well plates,
Species
human

Activity Assay

Product Number
Description
Species
Transglutaminase Assay Kit, sufficient for assays in two 96-well plates,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TGM2 (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Anti-TGM2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-Transglutaminase-2 (C-terminal) antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Transglutaminase-2 Antibody, FN binding domain Antibody, clone 4G3, clone 4G3, from mouse,
Species Reactivity
human
Application
flow cytometry
immunofluorescence

immunoprecipitation (IP)

western blot
Anti-TGM2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, human, mouse, pig, rat
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TGM2,
Species
human
MISSION® esiRNA, targeting mouse Tgm2,
Species
mouse