Skip to Content
MilliporeSigma

TARDBP

TAR DNA binding protein

Synonyms:
ALS10, TDP-43
Species:
UniProtKB ID:
Gene ID:
  • Human(23435) Summary: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]
  • Mouse(230908) TAR DNA binding protein
  • Rat(298648) TAR DNA binding protein
  • sheep(101114038) TAR DNA binding protein
  • domestic guinea pig(100718595) TAR DNA binding protein
  • naked mole-rat(101697585) TAR DNA binding protein
  • Horse(100051482) TAR DNA binding protein
  • cow(540632) TAR DNA binding protein
  • dog(478234) TAR DNA binding protein
  • Zebrafish(325052) TAR DNA binding protein
  • chicken(419453) TAR DNA binding protein
  • domestic cat(101097257) TAR DNA binding protein

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TARDBP antibody produced in mouse, clone 2E2-D3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Tdp43 Antibody, clone 3H8, clone 3H8, from mouse,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-TDP-43 Antibody, clone DB9, clone DB9, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-TARDBP Mouse mAb (2E2-D3), liquid, clone 2E2-D3, Calbiochem®,
Species Reactivity
human
Application
Anti-TDP-43 (C-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse TARDBP,
Species
mouse
MISSION® esiRNA, targeting human TARDBP,
Species
human