SSH1
slingshot protein phosphatase 1
Synonyms:
SSH1L
Species:
Human SSH1 (54434), Mouse Ssh1 (231637), Rat Ssh1 (304580), chicken SSH1 (427699), chicken SSH1 (101668825), domestic guinea pig Ssh1 (100718532), naked mole-rat Ssh1 (101714823), sheep SSH1 (101116093), Horse SSH1 (100066801), cow SSH1 (538233) ...More
UniProtKB ID:
Gene ID:
- Human(54434) Summary: The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
- Mouse(231637) slingshot homolog 1 (Drosophila)
- Rat(304580) slingshot protein phosphatase 1
- chicken(427699) slingshot homolog 1 (Drosophila)
- chicken(101668825) slingshot protein phosphatase 1
- domestic guinea pig(100718532) slingshot protein phosphatase 1
- naked mole-rat(101714823) slingshot protein phosphatase 1
- sheep(101116093) slingshot homolog 1 (Drosophila)
- Horse(100066801) slingshot homolog 1 (Drosophila)
- cow(538233) slingshot protein phosphatase 1
- domestic cat(101094543) slingshot homolog 1 (Drosophila)
- dog(477526) slingshot homolog 1 (Drosophila)
- chicken(101750781) slingshot protein phosphatase 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SSH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-SSH1 antibody produced in mouse, clone 2F9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-SSH1 Antibody, clone 12C6.1, clone 12C6.1, from mouse,
Species Reactivity
human
Application
western blot