SPTLC1
serine palmitoyltransferase, long chain base subunit 1
Synonyms:
HSAN1, HSN1, LBC1, LCB1, SPT1, SPTI
Species:
Human SPTLC1 (10558), Mouse Sptlc1 (268656), Rat Sptlc1 (361213), sheep SPTLC1 (101105721), dog SPTLC1 (484192), Zebrafish sptlc1 (553981), naked mole-rat Sptlc1 (101716616), chicken SPTLC1 (426145), Domestic Rabbit SPTLC1 (100344536), cow SPTLC1 (614165) ...More
UniProtKB ID:
Gene ID:
- Human(10558) Summary: Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Mouse(268656) serine palmitoyltransferase, long chain base subunit 1
- Rat(361213) serine palmitoyltransferase, long chain base subunit 1
- sheep(101105721) serine palmitoyltransferase, long chain base subunit 1
- dog(484192) serine palmitoyltransferase, long chain base subunit 1
- Zebrafish(553981) serine palmitoyltransferase, long chain base subunit 1
- naked mole-rat(101716616) serine palmitoyltransferase, long chain base subunit 1
- chicken(426145) serine palmitoyltransferase, long chain base subunit 1
- Domestic Rabbit(100344536) serine palmitoyltransferase, long chain base subunit 1
- cow(614165) serine palmitoyltransferase, long chain base subunit 1
- domestic guinea pig(100726468) serine palmitoyltransferase, long chain base subunit 1
- domestic cat(101087947) serine palmitoyltransferase, long chain base subunit 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SPTLC1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-SPTLC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-SPTLC1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
guinea pig, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-SPTLC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-SPTLC1 Antibody, serum, from rabbit,
Species Reactivity
chimpanzee, human
Application
western blot
esiRNA
Product Number
Description
Species