SOCS6
suppressor of cytokine signaling 6
Synonyms:
CIS-4, CIS4, HSPC060, SOCS-4, SOCS-6, SOCS4, SSI4, STAI4, STATI4
Species:
Human SOCS6 (9306), Mouse Socs6 (54607), Rat Socs6 (307200), sheep SOCS6 (101112276), Domestic Rabbit SOCS6 (100357417), Domestic Rabbit SOCS6 (100344911), domestic guinea pig Socs6 (100713080), naked mole-rat Socs6 (101716336), chicken SOCS6 (421020), dog SOCS6 (476171) ...More
UniProtKB ID:
Gene ID:
- Human(9306) Summary: The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq, Jul 2008]
- Mouse(54607) suppressor of cytokine signaling 6
- Rat(307200) suppressor of cytokine signaling 6
- sheep(101112276) suppressor of cytokine signaling 6
- Domestic Rabbit(100357417) suppressor of cytokine signaling 6
- Domestic Rabbit(100344911) suppressor of cytokine signaling 6
- domestic guinea pig(100713080) suppressor of cytokine signaling 6
- naked mole-rat(101716336) suppressor of cytokine signaling 6
- chicken(421020) suppressor of cytokine signaling 6
- dog(476171) suppressor of cytokine signaling 6
- Horse(100052089) suppressor of cytokine signaling 6
- domestic cat(101095049) suppressor of cytokine signaling 6
- cow(615146) suppressor of cytokine signaling 6
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SOCS6 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot