SNURF

SNRPN upstream reading frame

Synonyms:

Species:

UniProtKB ID:

Gene ID:

Human(8926) Summary: This gene encodes a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5' UTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known. [provided by RefSeq, Jul 2008]
Mouse(84704) SNRPN upstream reading frame
Rat(113938) SNRPN upstream reading frame
cow(282076) SNRPN upstream reading frame
dog(606883) SNRPN upstream reading frame
Domestic Rabbit(100009465) SNRPN upstream reading frame

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Product Number

Description

Species Reactivity

Application

Anti-SNURF (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,

Species Reactivity

human

Application

ELISA
western blot

Anti-SNURF antibody produced in rabbit, Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody,

Species Reactivity

human

Application

immunofluorescence