SHMT1
serine hydroxymethyltransferase 1 (soluble)
Synonyms:
CSHMT, SHMT
Species:
Human SHMT1 (6470), Mouse Shmt1 (20425), Rat Shmt1 (287379), chicken SHMT1 (416520), Zebrafish shmt1 (394021), naked mole-rat Shmt1 (101726020), domestic guinea pig Shmt1 (100733584), sheep SHMT1 (443544), Domestic Rabbit SHMT1 (100009405), cow SHMT1 (509002) ...More
UniProtKB ID:
Gene ID:
- Human(6470) Summary: This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
- Mouse(20425) serine hydroxymethyltransferase 1 (soluble)
- Rat(287379) serine hydroxymethyltransferase 1 (soluble)
- chicken(416520) serine hydroxymethyltransferase 1 (soluble)
- Zebrafish(394021) serine hydroxymethyltransferase 1 (soluble)
- naked mole-rat(101726020) serine hydroxymethyltransferase 1 (soluble)
- domestic guinea pig(100733584) serine hydroxymethyltransferase 1 (soluble)
- sheep(443544) serine hydroxymethyltransferase 1 (soluble)
- Domestic Rabbit(100009405) serine hydroxymethyltransferase 1 (soluble)
- cow(509002) serine hydroxymethyltransferase 1 (soluble)
- domestic cat(101086266) serine hydroxymethyltransferase 1 (soluble)
- dog(489536) serine hydroxymethyltransferase 1 (soluble)
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-SHMT1 antibody produced in mouse, clone 4F9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SHMT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SHMT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot