SERF1A
small EDRK-rich factor 1A (telomeric)
Synonyms:
4F5, FAM2A, H4F5, SERF1, SMAM1
Species:
Human SERF1A (8293), chicken SERF1A (769434), naked mole-rat Serf1a (101727447), cow SERF1A (526395), sheep SERF1A (101117789)
UniProtKB ID:
Gene ID:
- Human(8293) Summary: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The duplication region includes both a telomeric and a centromeric copy of this gene. Deletions of this gene, the telomeric copy, often accompany deletions of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients, and so it is thought that this gene may be a modifier of the SMA phenotype. The function of this protein is not known; however, it bears low-level homology with the RNA-binding domain of matrin-cyclophilin, a protein which colocalizes with small nuclear ribonucleoproteins (snRNPs) and the SMN1 gene product. Alternatively spliced transcripts have been documented but it is unclear whether alternative splicing occurs for both the centromeric and telomeric copies of the gene. [provided by RefSeq, Jul 2008]
- chicken(769434) small EDRK-rich factor 1A (telomeric)
- naked mole-rat(101727447) small EDRK-rich factor 1A (telomeric)
- cow(526395) small EDRK-rich factor 1A (telomeric)
- sheep(101117789) small EDRK-rich factor 1A (telomeric)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SERF1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
esiRNA
Product Number
Description
Species