RUNX2
runt-related transcription factor 2
Synonyms:
AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA
Species:
Human RUNX2 (860), Mouse Runx2 (12393), Rat Runx2 (367218), Goat RUNX2 (100861217), domestic guinea pig Runx2 (100734175), cow RUNX2 (536911), chicken RUNX2 (373919), Domestic Rabbit RUNX2 (100008943), Horse RUNX2 (100033890), domestic cat RUNX2 (101089612) ...More
UniProtKB ID:
Gene ID:
- Human(860) Summary: This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2008]
- Mouse(12393) runt related transcription factor 2
- Rat(367218) runt-related transcription factor 2
- Goat(100861217) runt-related transcription factor 2
- domestic guinea pig(100734175) runt-related transcription factor 2
- cow(536911) runt-related transcription factor 2
- chicken(373919) runt-related transcription factor 2
- Domestic Rabbit(100008943) runt-related transcription factor 2
- Horse(100033890) runt-related transcription factor 2
- domestic cat(101089612) runt-related transcription factor 2
- sheep(101115489) runt-related transcription factor 2
- dog(474923) runt-related transcription factor 2
- dog(449531) runt-related transcription factor 2
- naked mole-rat(101724767) runt-related transcription factor 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-RUNX2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0232, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CBFA1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-RUNX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-RUNX2 antibody produced in mouse, clone 1D8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Monoclonal Anti-RUNX2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0235, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
esiRNA
Product Number
Description
Species