RNF111
ring finger protein 111
Synonyms:
ARK
Species:
Human RNF111 (54778), Mouse Rnf111 (93836), Rat Rnf111 (300813), chicken RNF111 (374021), Zebrafish rnf111 (100151141), domestic guinea pig Rnf111 (100715851), cow RNF111 (540353), dog RNF111 (478323), Horse RNF111 (100054463), naked mole-rat Rnf111 (101696783) ...More
UniProtKB ID:
Gene ID:
- Human(54778) Summary: The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]
- Mouse(93836) ring finger 111
- Rat(300813) ring finger protein 111
- chicken(374021) ring finger protein 111
- Zebrafish(100151141) ring finger protein 111
- domestic guinea pig(100715851) ring finger protein 111
- cow(540353) ring finger protein 111
- dog(478323) ring finger protein 111
- Horse(100054463) ring finger protein 111
- naked mole-rat(101696783) ring finger protein 111
- sheep(101115967) ring finger protein 111
- domestic cat(101081225) ring finger protein 111
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RNF111 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot