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PURB

purine-rich element binding protein B

Synonyms:
PURBETA
Species:
Human PURB (5814), Mouse Purb (19291), Rat Purb (498407), naked mole-rat Purb (101713182), sheep PURB (101117840), chicken PURB (430546), domestic guinea pig Purb (100716526), domestic cat PURB (101099868), cow PURB (504276)
UniProtKB ID:
Q96QR8, A4D2L7
Gene ID:
  • Human(5814) Summary: This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008]
  • Mouse(19291) purine rich element binding protein B
  • Rat(498407) purine rich element binding protein B
  • naked mole-rat(101713182) purine-rich element binding protein B
  • sheep(101117840) purine-rich element binding protein B
  • chicken(430546) purine-rich element binding protein B
  • domestic guinea pig(100716526) purine-rich element binding protein B
  • domestic cat(101099868) purine-rich element binding protein B
  • cow(504276) purine-rich element binding protein B

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