PTPRU
protein tyrosine phosphatase, receptor type, U
Synonyms:
FMI, PCP-2, PTP, PTP-J, PTP-PI, PTP-RO, PTPPSI, PTPRO, PTPU2, R-PTP-PSI, R-PTP-U, hPTP-J
Species:
Human PTPRU (10076), Mouse Ptpru (19273), Rat Ptpru (116680), Zebrafish ptpru (100537682), chicken PTPRU (395153), domestic cat PTPRU (101092380), Horse PTPRU (100070588), cow PTPRU (535675), dog PTPRU (487328), sheep PTPRU (101108816) ...More
UniProtKB ID:
Gene ID:
- Human(10076) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported. [provided by RefSeq, Aug 2010]
- Mouse(19273) protein tyrosine phosphatase, receptor type, U
- Rat(116680) protein tyrosine phosphatase, receptor type, U
- Zebrafish(100537682) protein tyrosine phosphatase, receptor type, U
- chicken(395153) protein tyrosine phosphatase, receptor type, U
- domestic cat(101092380) protein tyrosine phosphatase, receptor type, U
- Horse(100070588) protein tyrosine phosphatase, receptor type, U
- cow(535675) protein tyrosine phosphatase, receptor type, U
- dog(487328) protein tyrosine phosphatase, receptor type, U
- sheep(101108816) protein tyrosine phosphatase, receptor type, U
- naked mole-rat(101725279) protein tyrosine phosphatase, receptor type, U
- domestic guinea pig(100715045) protein tyrosine phosphatase, receptor type, U
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PTPRU antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry