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PTPN4

protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)

Synonyms:
MEG, PTPMEG, PTPMEG1
Species:
UniProtKB ID:
Gene ID:
  • Human(5775) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. [provided by RefSeq, Jul 2008]
  • Mouse(19258) protein tyrosine phosphatase, non-receptor type 4
  • Rat(246116) protein tyrosine phosphatase, non-receptor type 4
  • chicken(424234) protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
  • cow(512883) protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
  • Domestic Rabbit(100352155) protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
  • domestic cat(101081915) protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
  • Horse(100060583) protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
  • dog(483882) protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
  • naked mole-rat(101701882) protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
  • domestic guinea pig(100714533) protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
  • sheep(101112629) protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PTPN4 antibody produced in mouse, clone 3C8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

Proteins

Product Number
Description
Species
MEG-1 Active human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ptpn4,
Species
mouse
MISSION® esiRNA, targeting mouse Ptpn4,
Species
mouse
MISSION® esiRNA, targeting human HMGXB3,
Species
human
MISSION® esiRNA, targeting human PTPN4,
Species
human