PRR5
proline rich 5 (renal)
Synonyms:
FLJ20185k, PP610, PROTOR-1, PROTOR1
Species:
Human PRR5 (55615), Mouse Prr5 (109270), Rat Prr5 (315189), Zebrafish prr5 (555584), chicken PRR5 (418237), Thale Cress PRR5 (832518), cow PRR5 (788925), domestic guinea pig Prr5 (101787415), dog PRR5 (100533463)
UniProtKB ID:
Gene ID:
- Human(55615) Summary: This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq, Nov 2010]
- Mouse(109270) proline rich 5 (renal)
- Rat(315189) proline rich 5 (renal)
- Zebrafish(555584) proline rich 5 (renal)
- chicken(418237) proline rich 5 (renal)
- Thale Cress(832518) pseudo-response regulator 5
- cow(788925) proline rich 5 (renal)
- domestic guinea pig(101787415) proline rich 5 (renal)
- dog(100533463) proline rich 5 (renal)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PRR5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry