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POT1

protection of telomeres 1

Synonyms:
HPOT1
Species:
UniProtKB ID:
Gene ID:
  • Human(25913) Summary: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
  • Rat(500054) protection of telomeres 1
  • chicken(404538) protection of telomeres 1 homolog (S. pombe)
  • Zebrafish(566847) protection of telomeres 1 homolog
  • domestic guinea pig(100725051) protection of telomeres 1
  • naked mole-rat(101698900) protection of telomeres 1
  • sheep(101107695) protection of telomeres 1 homolog (S. pombe)
  • cow(511292) protection of telomeres 1
  • Horse(100071610) protection of telomeres 1 homolog (S. pombe)
  • domestic cat(101097225) protection of telomeres 1 homolog (S. pombe)
  • dog(609119) protection of telomeres 1 homolog (S. pombe)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-POT1 Antibody, clone 43B7, ,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
Anti-POT1, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-POT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human POT1,
Species
human