PLCZ1
phospholipase C, zeta 1
Synonyms:
NYD-SP27, PLC-zeta-1, PLCzeta
Species:
Human PLCZ1 (89869), Mouse Plcz1 (114875), Rat Plcz1 (497197), domestic guinea pig Plcz1 (100716367), naked mole-rat Plcz1 (101709944), cow PLCZ1 (497026), chicken PLCZ1 (418182), dog PLCZ1 (486657), domestic cat PLCZ1 (101085554), sheep PLCZ1 (101122850)
UniProtKB ID:
Gene ID:
- Human(89869) Summary: The protein encoded by this gene is a member of the phosphoinositide-specific phospholipase C family. Members in this family, classified into six isotypes that are tissue- and organ-specific, hydrolyze phosphatidylinositol 4,5-bisphosphate just before the phosphate group to yield diacylglycerol and inositol 1,4,5-trisphosphate. This protein localizes to the acrosome in spermatozoa and elicits Ca(2+) oscillations and egg activation during fertilization that leads to early embryonic development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
- Mouse(114875) phospholipase C, zeta 1
- Rat(497197) phospholipase C, zeta 1
- domestic guinea pig(100716367) phospholipase C, zeta 1
- naked mole-rat(101709944) phospholipase C, zeta 1
- cow(497026) phospholipase C, zeta 1
- chicken(418182) phospholipase C, zeta 1
- dog(486657) phospholipase C, zeta 1
- domestic cat(101085554) phospholipase C, zeta 1
- sheep(101122850) phospholipase C, zeta 1
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