PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Synonyms:
PFK-2/FBPase-2
Species:
Human PFKFB2 (5208), Mouse Pfkfb2 (18640), Rat Pfkfb2 (24640), Horse PFKFB2 (100051146), naked mole-rat Pfkfb2 (101722273), domestic guinea pig Pfkfb2 (100713857), chicken PFKFB2 (419850), domestic cat PFKFB2 (101089572), dog PFKFB2 (480011), sheep PFKFB2 (101119324)
UniProtKB ID:
Gene ID:
- Human(5208) Summary: The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18640) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
- Rat(24640) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
- Horse(100051146) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
- naked mole-rat(101722273) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
- domestic guinea pig(100713857) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
- chicken(419850) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
- domestic cat(101089572) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
- dog(480011) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
- sheep(101119324) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
- cow(287019) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-6-Phosphofructo-2-Kinase, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-Fructose 6 Phosphate Kinase antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Phospho-PFKFB2-S483 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-PFKFB2 (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-phospho-Fructose 6 Phosphate Kinase (pSer483) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot