PDGFRB
platelet-derived growth factor receptor, beta polypeptide
Synonyms:
CD140B, IBGC4, IMF1, JTK12, PDGFR, PDGFR-1, PDGFR1
Species:
Human PDGFRB (5159), Mouse Pdgfrb (18596), Rat Pdgfrb (24629), domestic guinea pig Pdgfrb (100726506), naked mole-rat Pdgfrb (101721151), Zebrafish pdgfrb (559529), chicken PDGFRB (770488), dog PDGFRB (442985), domestic cat PDGFRB (101084600), cow PDGFRB (527165) ...More
UniProtKB ID:
Gene ID:
- Human(5159) Summary: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008]
- Mouse(18596) platelet derived growth factor receptor, beta polypeptide
- Rat(24629) platelet derived growth factor receptor, beta polypeptide
- domestic guinea pig(100726506) platelet-derived growth factor receptor, beta polypeptide
- naked mole-rat(101721151) platelet-derived growth factor receptor, beta polypeptide
- Zebrafish(559529) platelet-derived growth factor receptor beta
- chicken(770488) platelet-derived growth factor receptor, beta polypeptide
- dog(442985) platelet-derived growth factor receptor, beta polypeptide
- domestic cat(101084600) platelet-derived growth factor receptor, beta polypeptide
- cow(527165) platelet-derived growth factor receptor, beta polypeptide
- Domestic Rabbit(100342872) platelet-derived growth factor receptor, beta polypeptide
- sheep(101122783) platelet-derived growth factor receptor, beta polypeptide
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Custom Gene Products
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ELISA
Product Number
Description
Species
Phosphotyrosine PDGFRB / Platelet-derived Growth Factor Receptor Beta ELISA Kit, ,
Species
human
Human PDGF R β ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
MONOCLONAL ANTI-PDGFR antibody produced in mouse, clone 275CT1, crude ascites, buffered aqueous solution,
Species Reactivity
mouse
Application
western blot
Anti-PDGFRβ Antibody, clone 4A56, rabbit monoclonal, culture supernatant, clone 4A56, Upstate®,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot
western blot
Anti-PDGFR β antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-PDGFRB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Monoclonal Anti-CD140b antibody produced in mouse, clone 18A2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
PDGFRb active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Species
human
PDGFRβ(557-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
PDGFRβ Protein, active, 50 µg, Active, recombinant human PDGF Receptor β, residues 557-end, containing an N-terminal His6-tag, for use in Kinase Assays.,
Species
human
esiRNA
Product Number
Description
Species