PCDHGB2
protocadherin gamma subfamily B, 2
Synonyms:
PCDH-GAMMA-B2
Species:
Human PCDHGB2 (56103), Mouse Pcdhgb2 (93700), Rat Pcdhgb2 (680361), domestic cat PCDHGB2 (101097943), Horse PCDHGB2 (100072255), cow PCDHGB2 (100848197), cow PCDHGB2 (100337121), dog PCDHGB2 (100684038)
UniProtKB ID:
Gene ID:
- Human(56103) Summary: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
- Mouse(93700) protocadherin gamma subfamily B, 2
- Rat(680361) protocadherin gamma subfamily B, 2
- domestic cat(101097943) protocadherin gamma subfamily B, 2
- Horse(100072255) protocadherin gamma subfamily B, 2
- cow(100848197) protocadherin gamma subfamily B, 2
- cow(100337121) protocadherin gamma subfamily B, 2
- dog(100684038) protocadherin gamma subfamily B, 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PCDHGB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Monoclonal Anti-PCDHGB2 antibody produced in mouse, clone 6E9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot