PCDHGA9
protocadherin gamma subfamily A, 9
Synonyms:
PCDH-GAMMA-A9
Species:
Human PCDHGA9 (56107), Mouse Pcdhga9 (93717), Rat Pcdhga9 (252895), sheep PCDHGA9 (101104066), cow PCDHGA9 (101903888), domestic guinea pig Pcdhga9 (100721925), Horse PCDHGA9 (100146451), dog PCDHGA9 (100684594)
UniProtKB ID:
Gene ID:
- Human(56107) Summary: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
- Mouse(93717) protocadherin gamma subfamily A, 9
- Rat(252895) protocadherin gamma subfamily A, 9
- sheep(101104066) protocadherin gamma subfamily A, 9
- cow(101903888) protocadherin gamma subfamily A, 9
- domestic guinea pig(100721925) protocadherin gamma subfamily A, 9
- Horse(100146451) protocadherin gamma subfamily A, 9
- dog(100684594) protocadherin gamma subfamily A, 9
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PCDHGA9 antibody produced in mouse, clone 1G10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot