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PCDHGA8

protocadherin gamma subfamily A, 8

Synonyms:
PCDH-GAMMA-A8
Species:
Human PCDHGA8 (9708), Mouse Pcdhga8 (93716), Rat Pcdhga8 (364843), Zebrafish pcdhga8 (100536703), sheep PCDHGA8 (101103568), domestic guinea pig Pcdhga8 (100721363), dog PCDHGA8 (607612), cow PCDHGA8 (521340), domestic cat PCDHGA8 (101099427)
UniProtKB ID:
Q9Y5G5, A7MCZ4, O15039
Gene ID:
  • Human(9708) Summary: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
  • Mouse(93716) protocadherin gamma subfamily A, 8
  • Rat(364843) protocadherin gamma subfamily A, 8
  • Zebrafish(100536703) protocadherin gamma subfamily A, 8
  • sheep(101103568) protocadherin gamma subfamily A, 8
  • domestic guinea pig(100721363) protocadherin gamma subfamily A, 8
  • dog(607612) protocadherin gamma subfamily A, 8
  • cow(521340) protocadherin gamma subfamily A, 8
  • domestic cat(101099427) protocadherin gamma subfamily A, 8

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Antibodies

Product Number
Description
Species Reactivity
Application
WH0009708M1
Monoclonal Anti-PCDHGA8 antibody produced in mouse, clone 1C11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
SAB1410023
Anti-PCDHGA8 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot