PCDHA5
protocadherin alpha 5
Synonyms:
CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5
Species:
Human PCDHA5 (56143), Mouse Pcdha5 (12941), Rat Pcdha5 (393087), cow PCDHA5 (100847156), chicken PCDHA5 (497215), naked mole-rat Pcdha5 (101725566), domestic guinea pig Pcdha5 (100713870)
UniProtKB ID:
Gene ID:
- Human(56143) Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
- Mouse(12941) protocadherin alpha 5
- Rat(393087) protocadherin alpha 5
- cow(100847156) protocadherin alpha 5
- chicken(497215) protocadherin alpha 5
- naked mole-rat(101725566) protocadherin alpha 5
- domestic guinea pig(100713870) protocadherin alpha 5
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PCDHA5 antibody produced in mouse, clone 1E8, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-PCDHA5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
esiRNA
Product Number
Description
Species