PAX5
paired box 5
Synonyms:
BSAP
Species:
Human PAX5 (5079), Mouse Pax5 (18507), Rat Pax5 (500453), sheep PAX5 (101108719), domestic guinea pig Pax5 (100736213), naked mole-rat Pax5 (101700088), Zebrafish pax5 (60636), chicken PAX5 (387330), dog PAX5 (612021), domestic cat PAX5 (101089303) ...More
UniProtKB ID:
Gene ID:
- Human(5079) Summary: This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
- Mouse(18507) paired box gene 5
- Rat(500453) paired box 5
- sheep(101108719) paired box 5
- domestic guinea pig(100736213) paired box 5
- naked mole-rat(101700088) paired box 5
- Zebrafish(60636) paired box gene 5
- chicken(387330) paired box 5
- dog(612021) paired box 5
- domestic cat(101089303) paired box 5
- Horse(100055252) paired box 5
- cow(538371) paired box 5
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PAX-5 antibody, Rabbit monoclonal, clone SP34, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
chicken, dog, human, mouse
Application
flow cytometry
immunohistochemistry
immunohistochemistry
Anti-PAX-5 (paired box protein) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM331, purified immunoglobulin,
Species Reactivity
mouse, rat
Application
immunohistochemistry
PAX-5 (EP156) Rabbit Monoclonal Primary Antibody, ,
Species Reactivity
human
Application
immunohistochemistry
Anti-PAX5/BSAP antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
western blot
Anti-PAX5 Antibody, clone 4I0X4, Rabbit Monoclonal, ,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
esiRNA
Product Number
Description
Species