PADI1
peptidyl arginine deiminase, type I
Synonyms:
HPAD10, PAD1, PDI, PDI1
Species:
Human PADI1 (29943), Mouse Padi1 (18599), Rat Padi1 (54282), Horse PADI1 (100049961), domestic cat PADI1 (101085557), dog PADI1 (608443), chicken PADI1 (428171), cow PADI1 (618224), naked mole-rat Padi1 (101722077), domestic guinea pig Padi1 (100728246)
UniProtKB ID:
Gene ID:
- Human(29943) Summary: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
- Mouse(18599) peptidyl arginine deiminase, type I
- Rat(54282) peptidyl arginine deiminase, type I
- Horse(100049961) peptidyl arginine deiminase, type I
- domestic cat(101085557) peptidyl arginine deiminase, type I
- dog(608443) peptidyl arginine deiminase, type I
- chicken(428171) peptidyl arginine deiminase, type I
- cow(618224) peptidyl arginine deiminase, type I
- naked mole-rat(101722077) peptidyl arginine deiminase, type I
- domestic guinea pig(100728246) peptidyl arginine deiminase, type I
- sheep(101108201) peptidyl arginine deiminase, type I
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PADI1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Proteins
Product Number
Description
Species
PAD1, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
PADI-1 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Species
human
esiRNA
Product Number
Description
Species