OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
Synonyms:
Species:
Human OAS2 (4939), Mouse Oas2 (246728), Rat Oas2 (363938), domestic guinea pig Oas2 (100722402), naked mole-rat Oas2 (101698818), dog OAS2 (611051), Horse OAS2 (791250), cow OAS2 (529660), sheep OAS2 (101109915)
UniProtKB ID:
Gene ID:
- Human(4939) Summary: This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(246728) 2'-5' oligoadenylate synthetase 2
- Rat(363938) 2'-5' oligoadenylate synthetase 2
- domestic guinea pig(100722402) 2'-5'-oligoadenylate synthetase 2, 69/71kDa
- naked mole-rat(101698818) 2'-5'-oligoadenylate synthetase 2, 69/71kDa
- dog(611051) 2'-5'-oligoadenylate synthetase 2, 69/71kDa
- Horse(791250) 2'-5'-oligoadenylate synthetase 2, 69/71kDa
- cow(529660) 2'-5'-oligoadenylate synthetase 2, 69/71kDa
- sheep(101109915) 2'-5'-oligoadenylate synthetase 2, 69/71kDa
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-OAS2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, pig
Application
western blot
Anti-OAS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-OAS2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot
esiRNA
Product Number
Description
Species