NTSR2
neurotensin receptor 2
Synonyms:
NTR2
Species:
Human NTSR2 (23620), Mouse Ntsr2 (18217), Rat Ntsr2 (64636), naked mole-rat Ntsr2 (101706133), cow NTSR2 (539336), domestic cat NTSR2 (101093768), dog NTSR2 (482972), sheep NTSR2 (101104053)
UniProtKB ID:
Gene ID:
- Human(23620) Summary: The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008]
- Mouse(18217) neurotensin receptor 2
- Rat(64636) neurotensin receptor 2
- naked mole-rat(101706133) neurotensin receptor 2
- cow(539336) neurotensin receptor 2
- domestic cat(101093768) neurotensin receptor 2
- dog(482972) neurotensin receptor 2
- sheep(101104053) neurotensin receptor 2
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