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MilliporeSigma

NLRP13

NLR family, pyrin domain containing 13

Synonyms:
CLR19.7, NALP13, NOD14, PAN13
Species:
Human NLRP13 (126204), Horse NLRP13 (100057404), domestic cat NLRP13 (101087026), sheep NLRP13 (101109118), dog NLRP13 (484287), cow NLRP13 (529844)
UniProtKB ID:
Q86W25, Q7RTR5
Gene ID:
  • Human(126204) Summary: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]
  • Horse(100057404) NLR family, pyrin domain containing 13
  • domestic cat(101087026) NLR family, pyrin domain containing 13
  • sheep(101109118) NLR family, pyrin domain containing 13
  • dog(484287) NLR family, pyrin domain containing 13
  • cow(529844) NLR family, pyrin domain containing 13

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB3500556
Anti-NALP13 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunocytochemistry
immunofluorescence
western blot
HPA060459
Anti-NLRP13 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry