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NAE1

NEDD8 activating enzyme E1 subunit 1

Synonyms:
A-116A10.1, APPBP1, ula-1
Species:
UniProtKB ID:
Gene ID:
  • Human(8883) Summary: The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(234664) NEDD8 activating enzyme E1 subunit 1
  • Rat(84019) NEDD8 activating enzyme E1 subunit 1
  • Zebrafish(573336) nedd8 activating enzyme E1 subunit 1
  • chicken(415792) NEDD8 activating enzyme E1 subunit 1
  • chicken(776979) NEDD8 activating enzyme E1 subunit 1
  • dog(610026) NEDD8 activating enzyme E1 subunit 1
  • domestic cat(101086523) NEDD8 activating enzyme E1 subunit 1
  • naked mole-rat(101700870) NEDD8 activating enzyme E1 subunit 1
  • Horse(100065540) NEDD8 activating enzyme E1 subunit 1
  • sheep(101108941) NEDD8 activating enzyme E1 subunit 1
  • Domestic Rabbit(100350243) NEDD8 activating enzyme E1 subunit 1
  • domestic guinea pig(100725751) NEDD8 activating enzyme E1 subunit 1
  • cow(614491) NEDD8 activating enzyme E1 subunit 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-APPBP1 antibody produced in mouse, clone 4E8-H3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-NAE1 antibody produced in mouse, clone 2E9-D12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-NAE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-NAE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Nae1,
Species
mouse
MISSION® esiRNA, targeting human NAE1,
Species
human