MSH6
mutS homolog 6
Synonyms:
GTBP, GTMBP, HNPCC5, HSAP, p160
Species:
Human MSH6 (2956), Mouse Msh6 (17688), Thale Cress MSH6 (828147), fruit fly Msh6 (39654), Zebrafish msh6 (260437), chicken MSH6 (421291), domestic cat MSH6 (101082303), dog MSH6 (474585), cow MSH6 (540526), Domestic Rabbit MSH6 (100351645) ...More
UniProtKB ID:
Gene ID:
- Human(2956) Summary: This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. [provided by RefSeq, Jul 2008]
- Mouse(17688) mutS homolog 6 (E. coli)
- Thale Cress(828147) DNA mismatch repair protein MSH6
- fruit fly(39654) CG7003 gene product from transcript CG7003-RA
- Zebrafish(260437) mutS homolog 6 (E. coli)
- chicken(421291) mutS homolog 6 (E. coli)
- domestic cat(101082303) mutS homolog 6 (E. coli)
- dog(474585) mutS homolog 6 (E. coli)
- cow(540526) mutS homolog 6 (E. coli)
- Domestic Rabbit(100351645) mutS homolog 6 (E. coli)
- sheep(101107426) mutS homolog 6 (E. coli)
- naked mole-rat(101708261) mutS homolog 6 (E. coli)
- domestic guinea pig(100725043) mutS homolog 6 (E. coli)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MSH6 Antibody, clone 7M6T3, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
western blot
Monoclonal Anti-MSH6 antibody produced in mouse, clone 1F2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
Anti-MSH6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
Species Reactivity
human
Application
immunohistochemistry
Anti-MSH6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot