Skip to Content
MilliporeSigma

MAP4K2

mitogen-activated protein kinase kinase kinase kinase 2

Synonyms:
BL44, GCK, RAB8IP
Species:
UniProtKB ID:
Gene ID:
  • Human(5871) Summary: The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. [provided by RefSeq, Jul 2008]
  • Mouse(26412) mitogen-activated protein kinase kinase kinase kinase 2
  • Rat(293694) mitogen activated protein kinase kinase kinase kinase 2
  • domestic guinea pig(100722708) mitogen-activated protein kinase kinase kinase kinase 2
  • naked mole-rat(101710953) mitogen-activated protein kinase kinase kinase kinase 2
  • Zebrafish(100538181) mitogen-activated protein kinase kinase kinase kinase 2
  • dog(483759) mitogen-activated protein kinase kinase kinase kinase 2
  • domestic cat(101094701) mitogen-activated protein kinase kinase kinase kinase 2
  • Horse(100056001) mitogen-activated protein kinase kinase kinase kinase 2
  • cow(520058) mitogen-activated protein kinase kinase kinase kinase 2
  • sheep(101118145) mitogen-activated protein kinase kinase kinase kinase 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MAP4K2 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-MAP4K2 (ab1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, horse, human, mouse, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MAP4K2,
Species
human
MISSION® esiRNA, targeting mouse Map4k2,
Species
mouse