LILRB3
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
Synonyms:
CD85A, HL9, ILT-5, ILT5, LILRA6, LIR-3, LIR3, PIRB
Species:
Human LILRB3 (11025), Rat Lilrb3 (65146), Horse LILRB3 (100054321), cow LILRB3 (790139), cow LILRB3 (507024), domestic cat LILRB3 (101082610), cow LILRB3 (100139766), domestic guinea pig Lilrb3 (100728502), naked mole-rat Lilrb3 (101722653)
UniProtKB ID:
Gene ID:
- Human(11025) Summary: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Rat(65146) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
- Horse(100054321) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
- cow(790139) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
- cow(507024) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
- domestic cat(101082610) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
- cow(100139766) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
- domestic guinea pig(100728502) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
- naked mole-rat(101722653) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Lilrb3 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence