LGMN
legumain
Synonyms:
AEP, LGMN1, PRSC1
Species:
Human LGMN (5641), Mouse Lgmn (19141), Rat Lgmn (63865), dog LGMN (480232), chicken LGMN (423418), Zebrafish lgmn (406625), cow LGMN (281281), domestic cat LGMN (101098470), sheep LGMN (678680), naked mole-rat Lgmn (101698288)
UniProtKB ID:
Gene ID:
- Human(5641) Summary: This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008]
- Mouse(19141) legumain
- Rat(63865) legumain
- dog(480232) legumain
- chicken(423418) legumain
- Zebrafish(406625) legumain
- cow(281281) legumain
- domestic cat(101098470) legumain
- sheep(678680) legumain
- naked mole-rat(101698288) legumain
- domestic guinea pig(100718170) legumain
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-LGMN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-LGMN antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-Legumain (LGMN) Antibody, clone 6X5U6, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
western blot
Monoclonal Anti-LGMN antibody produced in mouse, clone M1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Monoclonal Anti-LGMN antibody produced in mouse, clone M2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
immunoprecipitation (IP)