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IAPP

islet amyloid polypeptide

Synonyms:
DAP, IAP
Species:
UniProtKB ID:
Gene ID:
  • Human(3375) Summary: Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. [provided by RefSeq, Apr 2011]
  • Mouse(15874) islet amyloid polypeptide
  • Rat(24476) islet amyloid polypeptide
  • dog(403909) islet amyloid polypeptide
  • domestic guinea pig(100135550) islet amyloid polypeptide
  • naked mole-rat(101702167) islet amyloid polypeptide
  • cow(100138011) islet amyloid polypeptide
  • sheep(101120402) islet amyloid polypeptide
  • Domestic Rabbit(100009489) islet amyloid polypeptide
  • chicken(396362) islet amyloid polypeptide
  • domestic cat(751513) islet amyloid polypeptide

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IAPP (N-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-Amylin antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-IAPP, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
immunohistochemistry
Anti-IAPP (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, horse, human, rabbit
Application
western blot
Anti-IAPP antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application

Proteins

Product Number
Description
Species
Diabetes Associated Peptide Amide human, ≥97% (HPLC),
Species
human
Acetyl-Diabetes Associated Peptide Fragment 8-37 amide trifluoroacetate salt, sequence human, ≥95% (HPLC),
Species
human