HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
Synonyms:
D6S2245E, FABG, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1, dJ1033B10.9
Species:
Human HSD17B8 (7923), Rat Hsd17b8 (361802), naked mole-rat Hsd17b8 (101726130), Zebrafish hsd17b8 (64815), cow HSD17B8 (532422), sheep HSD17B8 (101116612), domestic guinea pig Hsd17b8 (100736228), domestic cat HSD17B8 (101086309), dog HSD17B8 (607895)
UniProtKB ID:
Gene ID:
- Human(7923) Summary: In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]
- Rat(361802) hydroxysteroid (17-beta) dehydrogenase 8
- naked mole-rat(101726130) hydroxysteroid (17-beta) dehydrogenase 8
- Zebrafish(64815) hydroxysteroid (17-beta) dehydrogenase 8
- cow(532422) hydroxysteroid (17-beta) dehydrogenase 8
- sheep(101116612) hydroxysteroid (17-beta) dehydrogenase 8
- domestic guinea pig(100736228) hydroxysteroid (17-beta) dehydrogenase 8
- domestic cat(101086309) hydroxysteroid (17-beta) dehydrogenase 8
- dog(607895) hydroxysteroid (17-beta) dehydrogenase 8
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-HSD17B8 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-HSD17B8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-HSD17B8 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-HSD17B8 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-HSD17B8 antibody produced in mouse, clone 4F1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
esiRNA
Product Number
Description
Species