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HNMT

histamine N-methyltransferase

Synonyms:
HMT, HNMT-S1, HNMT-S2
Species:
UniProtKB ID:
Gene ID:
  • Human(3176) Summary: In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(140483) histamine N-methyltransferase
  • Rat(81676) histamine N-methyltransferase
  • chicken(424298) histamine N-methyltransferase
  • Zebrafish(445242) histamine N-methyltransferase
  • domestic cat(101093704) histamine N-methyltransferase
  • dog(476133) histamine N-methyltransferase
  • sheep(641310) histamine N-methyltransferase
  • cow(613413) histamine N-methyltransferase
  • domestic guinea pig(100135537) histamine N-methyltransferase
  • sheep(101102876) histamine N-methyltransferase

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-HNMT antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-HNMT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-HNMT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-HNMT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human HNMT (1),
Species
human
MISSION® esiRNA, targeting human HNMT (2),
Species
human
MISSION® esiRNA, targeting human HNMT (3),
Species
human