HIP1
huntingtin interacting protein 1
Synonyms:
HIP-I, ILWEQ
Species:
Human HIP1 (3092), Mouse Hip1 (215114), Rat Hip1 (192154), Thale Cress HIP1 (828363), fruit fly Hip1 (39450), dog HIP1 (489814), sheep HIP1 (101117042), cow HIP1 (505919), Zebrafish hip1 (793823), naked mole-rat Hip1 (101716682) ...More
UniProtKB ID:
Gene ID:
- Human(3092) Summary: The product of this gene is a membrane-associated protein that colocalizes with huntingtin. This protein has similarities to cytoskeleton proteins and its interaction with huntingtin is thought to play a functional role in the cell filament network. Loss of normal huntingtin-HIP1 interaction in Huntington disease may contribute to a defect in membrane-cytoskeletal integrity in the brain. This gene could help in the understanding of the normal function of huntingtin and also the pathogenesis of Huntington disease. It also has been implicated in the pathogenesis of hematopoietic malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
- Mouse(215114) huntingtin interacting protein 1
- Rat(192154) huntingtin interacting protein 1
- Thale Cress(828363) tetratricopeptide repeat protein
- fruit fly(39450) Huntingtin interacting protein 1
- dog(489814) huntingtin interacting protein 1
- sheep(101117042) huntingtin interacting protein 1
- cow(505919) huntingtin interacting protein 1
- Zebrafish(793823) huntingtin interacting protein 1
- naked mole-rat(101716682) huntingtin interacting protein 1
- domestic cat(101091918) huntingtin interacting protein 1
- domestic guinea pig(100718590) huntingtin interacting protein 1
- Horse(100061280) huntingtin interacting protein 1
- chicken(770683) huntingtin interacting protein 1
- Domestic Rabbit(100346836) huntingtin interacting protein 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-HIP1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-HIP1 antibody produced in mouse, clone 1F12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Huntingtin-Interacting Protein (HIP1) Antibody, Chemicon®, from rabbit,
Species Reactivity
human, rat
Application
western blot
Anti-HIP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-HIP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot