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GLRX

glutaredoxin (thioltransferase)

Synonyms:
GRX, GRX1
Species:
UniProtKB ID:
Gene ID:
  • Human(2745) Summary: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011]
  • Mouse(93692) glutaredoxin
  • Rat(64045) glutaredoxin (thioltransferase)
  • cow(515416) glutaredoxin (thioltransferase)
  • Zebrafish(449769) glutaredoxin (thioltransferase)
  • sheep(100147797) glutaredoxin (thioltransferase)
  • naked mole-rat(101701791) glutaredoxin (thioltransferase)
  • domestic cat(101081864) glutaredoxin (thioltransferase)
  • chicken(396069) glutaredoxin (thioltransferase)
  • dog(609246) glutaredoxin (thioltransferase)
  • domestic guinea pig(100713710) glutaredoxin (thioltransferase)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GLRX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-GLRX antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Glrx,
Species
mouse
MISSION® esiRNA, targeting human GLRX,
Species
human